Fidji Simo’s medical leave from OpenAI puts a spotlight on one of the most expansive roles in tech
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FORTUNE — Since Fidji Simo joined OpenAI in mid-2025, her work has been nonstop. What started with the title “CEO of Applications,” with a focus on commercializing OpenAI’s technology, quickly became much more than that.
OpenAI essentially split its organization in two, with Simo overseeing much of the company’s core business while CEO Sam Altman focuses on research and compute. In less than a year, Simo has shepherded the introduction of advertising into ChatGPT, the ongoing creation of an AI “superapp,” the introduction of ChatGPT Health, and the surprise acquisition of the tech news show TBPN. That’s hardly a complete list of her responsibilities; her title is now CEO, AGI deployment.
It’s a remarkable remit for any executive, and becomes all the more so when you learn more about what Simo has been navigating at the same time. OpenAI announced on Friday that Simo would be taking medical leave from the company for “the next several weeks.”
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